Labdoor analyzed 7 of the best-selling biotin supplements in the United States for biotin content and heavy metal (arsenic, cadmium, lead, mercury) contamination.
Overall, biotin measurements in this batch analysis ranged from 1,130 mcg to 10,700 mcg per serving, deviating from label claims by an average of 5%. 4 out of the 7 products recorded less biotin than claimed. All products passed heavy metal screenings.
For the US population, biotin deficiency is rare, but can lead to skin rash, hair loss, high cholesterol, and heart problems. To prevent deficiencies, the Adequate Intake (AI) per day for biotin has been defined as 30 mcg for most adults and 35 mcg for breastfeeding women. Claims that biotin intake above this level is effective for treating acne, eczema, and hair loss have not been proven1. Currently, biotin does not have an established Tolerable Upper Intake Level (UL) as reports of side effects are limited. Biotin has been found to be safe even at doses of up to 10000 mcg per day2.
Analytical Chemistry Methods: LC-UVDAD (biotin); ICP-MS (arsenic, cadmium, lead, mercury).
All 7 products tested passed testing for lead, cadmium, arsenic, and mercury contamination. This means that one serving of all of the protein products were shown to be under daily limits set by the United States Pharmacopeia.