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Updated: November 2, 2016

4 states and the District of Columbia have legalized marijuana for recreational use. With 20 other US states now allowing for some amount of cannabis possession for medical purposes, the rescheduling of cannabis is quickly spreading across the country.

Cannabis' neurobiological and cognitive effects are well known, but its active ingredients affect a variety of other bodily processes. For an overview of the global effects of cannabis–good and bad–read below:

Explaining Cannabis

Sources

  1. Co-author: Shoua Kue
  2. Co-author: Pasha Gurevich
  3. Preliminary, open-label, pilot study of add-on oral delta-9-tetrahydrocannabinol in chronic post-traumatic stress disorder - Clinical Drug Investigation
  4. Loss of striatal cannabinoid CB1 receptor function in attention-deficit/hyperactivity disorder mice with point-mutation of the dopamine transporter - European Journal of Neuroscience
  5. A molecular link between the active component of marijuana and Alzheimer's Disease pathology - ACS, Molecular Pharmaceutics
  6. The endogenous cannabinoid system regulates seizure frequency and duration in a model of temporal lobe epilepsy - The Journal of Pharmacology and Experimental Therapeutics
  7. Activation of CB2 receptors as a potential therapeutic target for migraine: evaluation in an animal model - The Journal of Headache and Pain
  8. Smoked cannabis for spasticity in multiple sclerosis: a randomized, placebo-controlled trial - Canadian Medical Association Journal
  9. Marijuana - National Multiple Sclerosis Society
  10. The impact of marijuana use on glucose, insulin, and insulin resistance among US adults - The American Journal of Medicine
  11. Association between marijuana exposure and pulmonary function over 20 years - The Journal of the American Medical Association
  12. Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis - Oxford Journals, Rheumatology
  13. Glaucoma and Marijuana Use - National Eye Institute (NEI), National Institutes of Health
  14. Cannabis hope for inflammatory bowel disease - ScienceDaily, courtesy of the British Pharmacological Society
  15. Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells - Molecular Cancer Therapeutics
  16. Drug Facts: Marijuana - National Institute on Drug Abuse, National Institutes of Health (NIH)
  17. What is bronchitis? - Mayo Clinic
  18. What science says about marijuana - The New York Times
  19. Adverse health effects of marijuana use - The New England Journal of Medicine
  20. Update: Adverse health effects of marijuana use - The New England Journal of Medicine
  21. Comparative epidemiology of tobacco, alcohol, controlled substances, and inhalants - Environmental and Clinical Psychopharmacology
     

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